PhD, Medical Biochemistry, Tokyo Medical and Dental University
MPhil, Molecular Cell Biology of Infectious Diseases, University of Ghana
BS, Biochemistry, University of Ghana
Role of RB1 & p53 loss in NEPC progression
Study of epigenetic lineage plasticity
Teachers and mentors who have altered my life: Lecturers at the Biochemistry Department at University of Ghana were very instrumental in my decision to be a research scientist. My parents modelled hard work and sacrifice; it is true, hard work pays off.
In my time off, I enjoy: Spending time with my wife and son.
What profession, other than your own, would you enjoy? I would probably have loved to be a farmer.
Sinclear, CK, Maruyama, J, Nagashima, S, Arimoto-Matsuzaki, K, Kuleape, JA, Iwasa, H, Nishina, H, & Hata, Y. Protein kinase Cα activation switches YAP1 from TEAD-mediated signaling to p73-mediated signaling. Cancer Science (2022). DOI: 10.1111/cas.15285
Kuleape JA, Hossain S, Sinclear CK, Shimizu T, Iwasa H, Maruyama J, Arimoto-Matsuzaki K, Nishina H, & Hata Y. DNA damage triggers the nuclear accumulation of RASSF6 tumor suppressor protein via CDK9 and BAF53 to regulate p53-target gene transcription. Mol Cell Biol (2021) DOI: 10.1128/MCB.00310-21.
Quaye O, Kuleape JA, Bonney EY, Puplampu P, & Tagoe EA. Imbalance of antioxidant enzymes activities and trace elements levels in Ghanaian HIV-infected patients. PLoS ONE (2019). DOI: 10.1371/journal.pone.0220181
Tagoe EA, Tagoe IN, Kuleape JA, Puplampu P, Amanquah S, Asare‐Anane H, & Quaye, O. Haptoglobin phenotypes with weak antioxidant capacity increase risk factors of cardiovascular disease in Ghanaian HIV‐infected patients on highly active antiretroviral therapy. Tropical Medicine and International Health (2019). DOI: 10.1111/tmi.13229
Kuleape JA, Tagoe EA, Puplampu P, Bonney EY, & Quaye O. Homozygous deletion of both GSTM1 and GSTT1 genes is associated with higher CD4+T cell counts in Ghanaian HIV patients. PLoS ONE (2018). DOI: 10.1371/journal.pone.0195954