Will Storck
Education
PhD, Molecular Biology, University of Oregon
BS, Chemistry, Western Michigan University
Research Interests
Elucidation of a role for E2F1 in neuroendocrine prostate cancer
Dysregulation of epigenetics and chromatin modifications in advanced prostate cancers
Funding
Prostate Cancer Foundation Young Investigator Award (2023-present)
UM Cancer Biology Training Program Fellowship (NCI T32) (2022)
Sheppard Family Postdoctoral Scholar
Contact
Email: wstorck@umich.edu
Mentors who have altered my life: My high school chemistry teacher, Mr. Upton, and my biology teachers, Mrs. Richardson and Mr. Fuller, were instrumental in fostering my enthusiasm for science. They all had a remarkable ability to make their respective subjects not only engaging but fun, even outside a budding interest in the sciences.
In my time off, I enjoy: Reading (especially sci-fi), cooking, playing my ukuleles/guitar, disc golfing, and playing boardgames with friends.
What profession, other than your own, would you enjoy? Had I not went into science, I think I would have liked to be a chef.
Select Publications
Kumaraswamy A, Duan Z, Flores D, Zhang C, Sehrawat A, Hu YM, Swaim OA, Rodansky E, Storck WK, Kuleape JA, Bedi K, Mannan R, Wang XM, Udager A, Ravikumar V, Bankhead A 3rd, Coleman I, Lee JK, Morrissey C, Nelson PS, Chinnaiyan AM, Rao A, Xia Z, Yates JA, & Alumkal JJ. LSD1 promotes prostate cancer reprogramming by repressing TP53 signaling independently of its demethylase function. JCI Insight (2023). DOI: 10.1172/jci.insight.167440
Storck WK, May AM, Westbrook TC, Duan Z, Morrissey C, Yates JA, & Alumkal JJ. The Role of Epigenetic Change in Therapy-Induced Neuroendocrine Prostate Cancer Lineage Plasticity. Frontiers in Endocrinology (2022). DOI: 10.3389/fendo.2022.926585
Kim DH, Sun D, Storck WK, Welker Leng KR, Jenkins C, Coleman DJ, Sampson DA, Guan X, Kumaraswamy A, Rodansky ES, Urrutia JA, Schwartzman J, Zhang C, Beltran H, Labrecque MP, Morrissey C, Lucas JM, Coleman I, Nelson PS, Corey E, Handelman SK, Sexton JZ, Aggarwal R, Abida W, Feng FY, Small EJ, Spratt DE, Bankhead III A, Rao A, Gesner EM, Attwell S, Lakhotia S, Campeau E, Yates JA, Xia Z, & Alumkal JJ. BET Bromodomain Inhibition Blocks an AR-Repressed, E2F1-Activated Treatment-Emergent Neuroendocrine Prostate Cancer Lineage Plasticity Program. Clinical Cancer Research (2021). DOI: 10.1158/1078-0432.CCR-20-4968
Storck WK, Bicocca VT, Rountree MR, Honda S, Ormsby T, & Selker EU. LSD1 prevents aberrant heterochromatin formation in Neurospora crassa. Nuc Acids Res (2020). DOI: 10.1093/nar/gkaa724
Storck WK, Abdulla SZ, Rountree MR, Bicocca VT, & Selker EU. A Light-Inducible Strain for Genome-Wide Histone Turnover Profiling in Neurospora crassa. Genetics (2020). DOI: 10.1534/genetics.120.303217
Klocko AD, Summers CA, Glover ML, Parrish R, Storck WK, McNaught KJ, Moss N, Gotting K, Stewart A, Morrison A, Payne L, Shiver A, Hatakeyama S, Selker EU. Selection and characterization of mutants defective in DNA methylation in Neurospora crassa. Genetics (2020). DOI: 10.1534/genetics.120.303471